An invariant Trypanosoma vivax vaccine antigen induces protective immunity

Nature, Published online: 26 May 2021; doi:10.1038/s41586-021-03597-x

Systemic genome-led vaccinology and a mouse model of Trypanosoma vivax infection identify protective invariant subunit vaccine antigens, and demonstrate the possibility of generating effective vaccines that induce long-lasting protection against trypanosome infections.