Equilibrium between nascent and parental MCM proteins protects replicating genomes

Nature, Published online: 21 October 2020; doi:10.1038/s41586-020-2842-3

Mother cells recycle parental MCMs and simultaneously synthesize nascent MCMs, both of which are inherited by daughter cells, in which the former are preferentially used to form active replisomes and the latter adjust the pace of replisome movement to minimize errors during DNA replication.