Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation

Nature, Published online: 29 May 2019; doi:10.1038/s41586-019-1244-x

An albumin-free culture system for the long-term ex vivo expansion of mouse haematopoietic stem cells produces 236- to 899-fold expansion, and generates cultures that robustly engraft in recipient mice without toxic pre-conditioning.

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