NATURE

Huge US institution cancels subscription with Elsevier Huge US institution cancels subscription with Elsevier , Published online: 28 February 2019; doi:10.1038/d41586-019-00758-x University of California and Dutch publisher fail to strike deal that would allow researchers to publish under open-access terms.

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Sexual harassment rife in Australian science, suggests first workplace survey Sexual harassment rife in Australian science, suggests first workplace survey , Published online: 28 February 2019; doi:10.1038/d41586-019-00736-3 One in two female respondents to a national poll has been sexually harassed at work.

NIH revoked funding from 14 scientists over sexual harassment last year NIH revoked funding from 14 scientists over sexual harassment last year, Published online: 28 February 2019; doi:10.1038/d41586-019-00753-2 The agency has faced sharp criticism over its handling of harassment allegations.

Publisher Correction: Damage-tolerant architected materials inspired by crystal microstructure Publisher Correction: Damage-tolerant architected materials inspired by crystal microstructure, Published online: 28 February 2019; doi:10.1038/s41586-019-0968-y Publisher Correction: Damage-tolerant architected materials inspired by crystal microstructure

Weekend lie-ins don’t compensate for week-long exhaustion Weekend lie-ins don’t compensate for week-long exhaustion, Published online: 28 February 2019; doi:10.1038/d41586-019-00723-8 Catching up on sleep over the weekend doesn’t undo the negative metabolic effects of sleep deprivation.

Spanish science reforms aim to make life easier for parents Spanish science reforms aim to make life easier for parents, Published online: 28 February 2019; doi:10.1038/d41586-019-00649-1 Researchers welcome changes that should also make it easier to hire researchers and buy equipment.

Walter Munk (1917-2019) Walter Munk (1917-2019), Published online: 28 February 2019; doi:10.1038/d41586-019-00750-5 A founder of modern oceanography.

Night-vision ‘super-mice’ created using light-converting nanoparticles Night-vision ‘super-mice’ created using light-converting nanoparticles, Published online: 28 February 2019; doi:10.1038/d41586-019-00735-4 The particles bind to photoreceptors in the eyes and convert infrared wavelengths to visible light.

RNA snippets snare protein linked to degeneration of neurons RNA snippets snare protein linked to degeneration of neurons, Published online: 28 February 2019; doi:10.1038/d41586-019-00700-1 Technique ties up an innocuous protein before it gathers into dangerous clumps.

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Paul Nurse on Brexit: ‘UK is sleepwalking into a disaster’ Paul Nurse on Brexit: ‘UK is sleepwalking into a disaster’, Published online: 28 February 2019; doi:10.1038/d41586-019-00694-w As departure day approaches, chief of top UK lab says he fears science will drop off the government’s agenda.

Managing nitrogen to restore water quality in China Managing nitrogen to restore water quality in China, Published online: 28 February 2019; doi:10.1038/s41586-019-1001-1 Managing nitrogen to restore water quality in China

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Big pharma is embracing open-access publishing like never before Big pharma is embracing open-access publishing like never before, Published online: 28 February 2019; doi:10.1038/d41586-019-00610-2 Proportion of open-access publications with authors from the pharmaceutical industry doubled between 2009 and 2016.

‘Gene-edited babies’ is one of the most censored topics on Chinese social media ‘Gene-edited babies’ is one of the most censored topics on Chinese social media, Published online: 28 February 2019; doi:10.1038/d41586-019-00607-x Other sensitive topics in 2018 include a vaccine scandal and a physician jailed for criticizing traditional Chinese medicine.

Manfred Eigen (1927–2019) Manfred Eigen (1927–2019), Published online: 28 February 2019; doi:10.1038/d41586-019-00731-8 Observer of fast reactions in the laboratory and in life.

Scientists criticize Australia’s ‘questionable’ climate policy Scientists criticize Australia’s ‘questionable’ climate policy, Published online: 28 February 2019; doi:10.1038/d41586-019-00725-6 They say the Aus$3.5-billion package will not help the country meet its Paris emissions targets.

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Pioneering 'live-code' article allows scientists to play with each other’s results Pioneering 'live-code' article allows scientists to play with each other’s results, Published online: 28 February 2019; doi:10.1038/d41586-019-00724-7 eLife's prototype lets scientists modify the software underlying figures to validate, build on, or better understand the work.

Micro-droplets in minuscule channels need no help to get ahead Micro-droplets in minuscule channels need no help to get ahead, Published online: 27 February 2019; doi:10.1038/d41586-019-00701-0 Channel design allows fluid droplets to self-propel in a controlled manner.

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Social parasitism as an alternative reproductive tactic in a cooperatively breeding cuckoo Social parasitism as an alternative reproductive tactic in a cooperatively breeding cuckoo, Published online: 27 February 2019; doi:10.1038/s41586-019-0981-1 Mixed-effects logistic regression modelling of a dataset of individual reproductive behaviours shows fitness pay-offs of cooperative versus mixed cooperative and parasitic reproductive strategies are approximately equal in female greater anis (Crotophaga major).

Author Correction: Systems of mechanized and reactive droplets powered by multi-responsive surfactants Author Correction: Systems of mechanized and reactive droplets powered by multi-responsive surfactants, Published online: 27 February 2019; doi:10.1038/s41586-019-0930-z Author Correction: Systems of mechanized and reactive droplets powered by multi-responsive surfactants

Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma, Published online: 27 February 2019; doi:10.1038/s41586-019-0987-8 A subtype of early-stage hepatocellular carcinoma characterized by disrupted cholesterol homeostasis and associated with a poor prognosis responds to treatment with the SOAT1 inhibitor avasimibe in a patient-derived xenograft mouse model.

Colouration by total internal reflection and interference at microscale concave interfaces Colouration by total internal reflection and interference at microscale concave interfaces, Published online: 27 February 2019; doi:10.1038/s41586-019-0946-4 A mechanism for creating patterns of iridescent structural colour by total internal reflection of light beams along a concave optical interface leading to interference is described, for complex microscopic systems and for systems as simple as condensed water drops.

Promising ways to encode and manipulate quantum information Promising ways to encode and manipulate quantum information, Published online: 27 February 2019; doi:10.1038/d41586-019-00647-3 Quantum computers require controlled encoding to protect computations from environmental noise. Two experiments have achieved such encoding using what are known as infinite-dimensional quantum systems.

Complete biosynthesis of cannabinoids and their unnatural analogues in yeast Complete biosynthesis of cannabinoids and their unnatural analogues in yeast, Published online: 27 February 2019; doi:10.1038/s41586-019-0978-9 Genetic engineering of yeast enables the production of cannabinoids and cannabinoid analogues from the simple sugar galactose, without the need to cultivate Cannabis.

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche Breast cancer cells rely on environmental pyruvate to shape the metastatic niche, Published online: 27 February 2019; doi:10.1038/s41586-019-0977-x Exogenous pyruvate is needed for breast cancer cells to form metastases, and the inhibition of pyruvate metabolism impairs collagen hydroxylation and the growth of lung metastases in different mouse models.

Encoding a qubit in a trapped-ion mechanical oscillator Encoding a qubit in a trapped-ion mechanical oscillator, Published online: 27 February 2019; doi:10.1038/s41586-019-0960-6 A single logical qubit is encoded, manipulated and read out using a superposition of displaced squeezed states of the harmonic motion of a trapped calcium ion.

A newly discovered stem cell that keeps bones growing A newly discovered stem cell that keeps bones growing, Published online: 27 February 2019; doi:10.1038/d41586-019-00527-w Bone elongation requires the maintenance of a growth plate of cartilage. Two studies have now identified stem cells specific to this structure that give rise to both cartilage cells and bone-marrow stem cells.

Comprehensive search for topological materials using symmetry indicators Comprehensive search for topological materials using symmetry indicators, Published online: 27 February 2019; doi:10.1038/s41586-019-0937-5 An algorithm based on symmetry indicators is used to search a crystallographic database and finds thousands of candidate topological materials, which could be exploited in next-generation electronic devices.

Taking connected mobile-health diagnostics of infectious diseases to the field Taking connected mobile-health diagnostics of infectious diseases to the field, Published online: 27 February 2019; doi:10.1038/s41586-019-0956-2 Combining mobile phone technologies with infectious disease diagnostics can increase patients’ access to testing and treatment and provide public health authorities with new ways to monitor and control outbreaks of infectious diseases.

An integrative systems genetic analysis of mammalian lipid metabolism An integrative systems genetic analysis of mammalian lipid metabolism, Published online: 27 February 2019; doi:10.1038/s41586-019-0984-y The integration of liver and plasma quantitative lipidomic and proteomic data from 107 distinct mouse strains provides important insights into regulators of mammalian lipid metabolism.

Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations, Published online: 27 February 2019; doi:10.1038/s41586-019-0876-1 Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations

Colour from colourless droplets Colour from colourless droplets, Published online: 27 February 2019; doi:10.1038/d41586-019-00638-4 Iridescent colours have been observed to be reflected from specially designed droplets of colourless liquids, with the reflected colour depending on the viewing angle. The finding reveals a curious mechanism for creating coloration.

Catalogue of topological electronic materials Catalogue of topological electronic materials, Published online: 27 February 2019; doi:10.1038/s41586-019-0944-6 Topological materials are thought to be scarce, but an algorithm that diagnoses nontrivial topology in nonmagnetic materials finds the opposite: more than 30 per cent of the 26,688 materials studied are topological.

Structure of the IFNγ receptor complex guides design of biased agonists Structure of the IFNγ receptor complex guides design of biased agonists, Published online: 27 February 2019; doi:10.1038/s41586-019-0988-7 The X-ray structure of the hexameric complex of interferon-γ bound to its receptors is solved at 3.25 Å resolution, providing a basis for engineering variants of interferon-γ that enable decoupling of its immunomodulatory functions.

Entanglement of bosonic modes through an engineered exchange interaction Entanglement of bosonic modes through an engineered exchange interaction, Published online: 27 February 2019; doi:10.1038/s41586-019-0970-4 Two superconducting cavity modes are entangled using an exponential-SWAP logic gate.

Battling disease by giving mosquitoes an antimalarial drug Battling disease by giving mosquitoes an antimalarial drug, Published online: 27 February 2019; doi:10.1038/d41586-019-00648-2 Insecticides that kill mosquitoes have helped to fight malaria, but insecticide resistance is rising. Treating mosquitoes with drugs that target the disease-causing parasite offers another way of tackling malaria.