Closed mitosis requires local disassembly of the nuclear envelope

Nature, Published online: 26 August 2020; doi:10.1038/s41586-020-2648-3

In a study performed in Schizosaccharomyces pombe, ‘closed mitosis’ is shown to occur via local disassembly of the nuclear envelope within the narrow bridge connecting segregating daughter nuclei, and a key role is identified for Les1, which restricts nuclear envelope breakdown to the bridge.