Mechanisms of BRCA1–BARD1 nucleosome recognition and ubiquitylation
Nature, Published online: 28 July 2021; doi:10.1038/s41586-021-03716-8
The authors elucidate the mechanisms for the ubiquitylation specificity and recruitment of the ubiquitin ligase complex BRCA1–BARD1 to damaged DNA within chromatin to facilitate homologous recombination.
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