BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination
Nature, Published online: 28 July 2021; doi:10.1038/s41586-021-03776-w
A tandem BRCT-domain-associated ubiquitin-dependent recruitment motif in BARD1 recruits BRCA1 to DNA double-strand breaks (DSBs) to promote homologous recombination and antagonize the 53BP1 DSB repair pathway that mediates non-homologous end joining.
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