Host ANP32A mediates the assembly of the influenza virus replicase

Nature, Published online: 18 November 2020; doi:10.1038/s41586-020-2927-z

Structural and biochemical studies of influenza virus RNA polymerase in complex with host acidic nuclear phosphoprotein 32 (ANP32) show how ANP32-mediated polymerase dimerization enables the replication of influenza viral RNA in a host-dependent manner.

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