A GPR174–CCL21 module imparts sexual dimorphism to humoral immunity

Nature, Published online: 25 December 2019; doi:10.1038/s41586-019-1873-0

Male and female B cells show differing abilities to localize and contribute to germinal centres, in a way that depends on the G-protein-coupled guidance receptor GPR174 and its chemokine ligand CCL21.