CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy

Nature, Published online: 31 July 2019; doi:10.1038/s41586-019-1456-0

CD24 interacts with the tumour-associated-macrophage receptor Siglec-10 to inhibit the macrophage-mediated clearance of cancer cells, revealing a new ‘don’t eat me’ signal as a potential target for cancer immunotherapy.

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