Distinct descending motor cortex pathways and their roles in movement

Distinct descending motor cortex pathways and their roles in movement

Distinct descending motor cortex pathways and their roles in movement, Published online: 31 October 2018; doi:10.1038/s41586-018-0642-9

Transcriptional profiling and axonal reconstructions identify two types of pyramidal tract neuron in the motor cortex: one type projects to thalamic regions and produces early and persistent preparatory activity, and the other type projects to motor centres in the medulla and produces motor commands.