A ‘don’t eat me’ immune signal protects neuronal connections

A ‘don’t eat me’ immune signal protects neuronal connections

A ‘don’t eat me’ immune signal protects neuronal connections, Published online: 29 October 2018; doi:10.1038/d41586-018-07165-8

During development, some synaptic connections between neurons are removed by immune cells called microglia, and others are retained. The discovery of a ‘don’t eat me’ signal that prevents excess pruning sheds light on this process.