A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Nature, Published online: 03 August 2022; doi:10.1038/s41586-022-05022-3

Biochemical and lipidomic analyses identify an anti-ferroptotic function of vitamin K and reveal ferroptosis suppressor protein 1 (FSP1) as the enzyme mediating warfarin-resistant vitamin K reduction in the canonical vitamin K cycle.

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