Molecular basis for DarT ADP-ribosylation of a DNA base

Nature, Published online: 18 August 2021; doi:10.1038/s41586-021-03825-4

Structural and mechanistic data of the ADP-ribosyltransferase DarT demonstrate the role of ADP-ribosylation of DNA by this enzyme in generating toxicity and regulating cellular signalling processes in bacteria.