Discovery and engineering of colchicine alkaloid biosynthesis
Nature, Published online: 22 July 2020; doi:10.1038/s41586-020-2546-8
Discovery of a near-complete colchicine biosynthetic pathway enables the engineered production of the tropolone-containing alkaloid N-formyldemecolcine from amino acid precursors in Nicotiana benthamiana.
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