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Showing posts from July, 2020

Look beyond publication records, urges report

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02294-5 Science Europe recommends assessing societal impact and contributions to knowledge and policy when awarding grants and promotions.

Daily Briefing: Weird immune systems allow mating anglerfish to fuse together

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02292-7 Genetic analysis sheds new light on the bizarre mating ritual of the deep-sea fish. Plus: the challenges China’s coronavirus vaccines face and why skin grows bigger as you stretch it.

‘It’s like we’re going back 30 years’: how the coronavirus is gutting diversity in science

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02288-3 The pandemic is sabotaging the careers of researchers from under-represented groups, but institutions can help to staunch the outflow.

Photo Of The Day By Lori McLellan

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Photo By Lori McLellan Today’s Photo Of The Day is “Meet in the Middle” by Lori McLellan. Photo of the Day is chosen from various OP galleries, including Assignments ,  Galleries  and the  OP Contests . Assignments have weekly winners that are featured on the OP website homepage,  Facebook ,  Twitter  and  Instagram . To get your photos in the running, all you have to do is submit them. The post Photo Of The Day By Lori McLellan appeared first on Outdoor Photographer .

The particle accelerator that’s serious about recycling

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02262-z Most linear accelerators are energy hogs, but a new model recovers waste energy that can be ploughed back into the system.

How African scientists can give back to their home continent

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02267-8 Rafiou Agoro’s early-career experiences in France and the United States inspired him to mentor colleagues in Africa and those whose careers also took them overseas.

A CRISPR first produces squid as clear as glass

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02242-3 The creation of spotless cephalopods hints that squid could make a good model organism for applying CRISPR to brain research.

China’s coronavirus vaccines are leaping ahead – but face challenges as virus wanes

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Nature, Published online: 31 July 2020; doi:10.1038/d41586-020-02244-1 Companies could struggle to enrol enough trial participants, or gather enough data to convince regulatory agencies that the shots work.

Gut microbes and stress team up to make a painful disease worse

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02263-y A type of gut bacterium worsens the inflammatory response and cardiovascular problems in mice.

Daily Briefing: NASA’s Perseverance rover blasts off for Mars

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02271-y The most complex rover ever sent to the red planet will attempt to collect rock samples for return to Earth. Plus: the origin of Stonehenge’s giant stones, and three questions to ask yourself before quitting your PhD.

University redundancies, furloughs and pay cuts might loom amid the pandemic, survey finds

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02265-w Academic administrators are mostly optimistic about the effects of COVID-19 on institutional finances, but others predict tough times.

Shooting A Concept Assignment Winner Rene Gruber

Congratulations to Rene Gruber for winning the Shooting A Concept Assignment with the image, “Illuminate the Night.” See more of Gruber’s work at www.renegruber.com . View the winning image and a selection of submissions in the gallery below. And be sure to check out our current photography assignment  here  and enter your best shots! [ See image gallery at www.outdoorphotographer.com ] The post Shooting A Concept Assignment Winner Rene Gruber appeared first on Outdoor Photographer .

University redundancies, furloughs and pay cuts might loom amid the pandemic, survey finds

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02265-w Academic administrators are mostly optimistic about the effects of COVID-19 on institutional finances, but others predict tough times.

Photo Of The Day By Beth Young

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Photo By Beth Young Today’s Photo Of The Day is “Colusa County Flowers and Hills” by Beth Young. Location: Colusa County, California. “Last weekend, my husband and I ventured out for a drive to nearby rural Colusa County,” says Young. “Our favorite wildflower spot was devoid of my beloved poppies, but we found this massive field of purple lupine and yellow wildflowers. With partly cloudy skies, the dappled light danced across the green hills in the distance and I elected to use the telephoto for a more intimate scene.” Canon EOS 5D Mark IV. Exposure: 1/1000 sec., f/16, ISO 2000. See more of Beth Young’s photography at www.optimalfocusphotography.com . Photo of the Day is chosen from various OP galleries, including Assignments ,  Galleries  and the  OP Contests . Assignments have weekly winners that are featured on the OP website homepage,  Facebook ,  Twitter  and  Instagram . To get your photos in the running, all you have to do is submit them....

DNA targeting and interference by a bacterial Argonaute nuclease

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Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2605-1 DNA targeting and interference by a bacterial Argonaute nuclease

Microbiota-derived metabolite promotes HDAC3 activity in the gut

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Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2604-2 Microbiota-derived metabolite promotes HDAC3 activity in the gut

NASA has launched the most ambitious Mars rover ever built: here’s what happens next

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02257-w Perseverance will stow away rocks for eventual delivery to Earth, and will listen for Martian sounds for the first time.

Virologists divided over plans to change virus-naming rules during the pandemic

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02243-2 Researchers say now is bad time to introduce a system for naming viral species, when scientists are focused on the coronavirus outbreak.

This super ‘sponge’ releases steam when the Sun shines

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Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02255-y A curious gel can soak up water vapour from the air and swell to enormous size without bursting.

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

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Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2607-z Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

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Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2608-y ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

Realize Your Vision

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Nothing is as thrilling as the moment when all of your planning and preparation to get “the shot” pays off, right before your eyes. But the most lasting satisfaction comes from holding an archival photographic print that faithfully reproduces that vision. A perfect sunrise over the landscape. Polar bears dancing in the tundra. Your best photographs deserve the finest printing capabilities. The incredible resolution and color reproduction of today’s digital cameras capture the details necessary to create prints with a tonal range and subtlety of hue never before possible—if your printer is equally obsessed with those details. Intelligent Output Control With Smart Nozzles Canon imagePROGRAF PRO-1000 (left) and imagePROGRAF PRO-300 (right). Canon’s imagePROGRAF PRO-300 and imagePROGRAF PRO-1000 are no-compromise professional printers designed to fit in your home or small studio. Their stunning print quality is made possible by Canon’s FINE print head, an ink delivery system that p...

Perspectives on ENCODE

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2449-8 The authors summarize the history of the ENCODE Project, the achievements of ENCODE 1 and ENCODE 2, and how the new data generated and analysed in ENCODE 3 complement the previous phases.

Mechanisms of stretch-mediated skin expansion at single-cell resolution

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2555-7 Single-cell analysis in a mouse model of skin stretching shows that stretching causes a transient expansion bias in a population of epidermal stem cells, which is associated with chromatin remodelling and changes in transcriptional profiles.

New class of molecule targets proteins outside cells for degradation

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02211-w Molecules have previously been made that induce protein destruction inside cells. A new class of molecule now induces the degradation of membrane and extracellular proteins — opening up avenues for drug discovery.

Photo Of The Day By Jeff Nigro

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Photo By Jeff Nigro Today’s Photo Of The Day is “Moraine Lake” by Jeff Nigro. Location: Banff National Park, Alberta. Photo of the Day is chosen from various OP galleries, including Assignments ,  Galleries  and the  OP Contests . Assignments have weekly winners that are featured on the OP website homepage,  Facebook ,  Twitter  and  Instagram . To get your photos in the running, all you have to do is submit them. The post Photo Of The Day By Jeff Nigro appeared first on Outdoor Photographer .

Bacteria-eating viruses could provide a route to stability in cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02109-7 Phage therapy is broadening the treatment landscape for people with drug-resistant infections.

Gene therapy could offer an inclusive cure for cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02111-z After three decades of false starts, gene therapy against the disease is in new clinical trials — and there is even hope of a cure.

How much protein function needs to be restored in cystic fibrosis?

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02114-w Knowing the percentage of function that is required to eliminate disease symptoms could help to shape treatment in the coming years and ensure sufferers don’t slip through the net.

A simple test could extend cystic-fibrosis treatments to those left behind

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02107-9 Sweat-chloride measurements could be used to develop and approve drugs for rare mutations in cystic fibrosis.

Cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02105-x Innovative therapies are bringing hope to people with this inherited lung disorder.

The coronavirus pandemic has forced rapid changes in care protocols for cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02112-y Lockdowns have accelerated the drive towards telemedicine for people with cystic fibrosis — but the system needs critical appraisal.

The gender gap in cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02110-0 Despite advances in therapies for people with the genetic disease, women seem to have poorer outcomes.

Pluto’s dark side spills its secrets — including hints of a hidden ocean

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02082-1 Images of the dwarf planet’s far side are revealing possible signs of liquid water, mysterious shards of ice and new theories for the frigid world’s birth.

In utero intervention to stem the damage of cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02108-8 To safeguard organs, therapies must tackle this hereditary disease in the womb.

Research round-up: Cystic fibrosis

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02115-9 Molecular pathways of inflammation, the cystic fibrosis microbiome and other highlights from clinical trials and laboratory studies.

Cystic fibrosis drugs target the malformed proteins at the root of the disease

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02106-w New combinations of molecules put many patients on the path to good health. But those with rarer mutations are, for now, left behind.

Living, breathing proof

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02113-x A cadre of older patients with cystic fibrosis have defied the life expectancy associated with their illness. They’re inspiring and educating others about surviving with the disease long-term.

Trash can rap

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02245-0 Something fresh.

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2598-9 SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2600-6 Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2599-8 A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2601-5 Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

Dinosaur retraction, Neanderthal pain and EU budget woe

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02204-9 The latest science news, in brief.

The quantum Hall effect continues to reveal its secrets to mathematicians and physicists

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Nature, Published online: 29 July 2020; doi:10.1038/d41586-020-02230-7 A transformative experiment is yielding fresh insights 40 years after the effect’s discovery — and energizing transdisciplinary collaborations.

Publisher Correction: Extensive signal integration by the phytohormone protein network

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2585-1 Publisher Correction: Extensive signal integration by the phytohormone protein network

Author Correction: The dental proteome of Homo antecessor

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Nature, Published online: 29 July 2020; doi:10.1038/s41586-020-2580-6 Author Correction: The dental proteome of Homo antecessor